Transfer Factors Study with Autistic Children

These children were given three capsules containing transfer factors, three times daily, for three months. Each patient was assessed prior to the treatment, six weeks into the study, and at the completion of the three-month study.... more

Transfer Factors and HIV

Included in this study were 25 HIV-infected patients (20 male and 5 female), ages 19 to 56 (15 patients ages 21-25). Individuals were classified according to V.I. Pokrovskys classification (1989) for HIV-infection... more

Transfer Factors and Inflammation

OBJECTIVE: To investigate i) whether the Dialyzable Leukocyte Extract (DLE) modulates the production of proinflammatory cytokines in leukocytes activated by the bacterial cell wall components lipopolysaccharide (LPS), lipoteichoic acid (LTA), and peptidoglycan (PGN); ii) the effect of DLE on LPS-stimulated endothelial cells;... more

Transfer Factors and Autoimmune Conditions

Arthritis...

Multiple Sclerosis...

Diabetes Mellitus...

Atopic Dermatitis...

Chronic Fatigue Syndrome...

... more

Transfer Factors and Diabetes

Background Intensive lifestyle interventions can reduce the incidence of type 2 diabetes in people with impaired glucose tolerance, but how long these benefits extend beyond the period of active intervention, and whether such interventions reduce the risk of cardiovascular disease (CVD) and mortality, is unclear..... more

 

 

 


INCREASED TUMOR NECROSIS FACTOR ALPHA (TNF-a) AND NATURAL KILLER CELL (NK) FUNCTION USING AN INTEGRATIVE APPROACH IN LATE STAGE CANCERS 06/01/2002

References
1    SEER (Surveillance, Epidemiology, and End Results) Cancer Statistics Review, National Cancer Institute, 1996.

2  Boik J. Cancer and Natural Medicine,  Oregon Medical Press, Princeton, Minnesota, 1996, 3

3  Moss R. Cancer Therapy: The Independent Consumer's Guide,  Equinox Press, Brooklyn, 1996,

4  Korbelik M., Sun J., Cancer Treatment by Photodynamic Therapy Combined with Adoptive Immunotherapy using Genetically Altered Natural Killer Cell Line, Int. J. Cancer, 93 (2001) 269–274.

5  Miki T., Yano S., Hanibuchi M., Sone S., Bone Metastases Model with Multiorgan Dissemination of Human Small Cell Lung Cancer (SBC-5) Cells in Natural Killer Cell Delpleted Mice, Oncol. Res., 12 (2001) 209–217.

6  Zhang M., Tracey K. Tumor Necrosis Factor, The Cytokine Handbook,  3, Academic Press Ltd., 1998, pp. 517–548.

7  Marr R., Hitt M., Muller WJ., Gauldie J., Graham FL., Tumour Therapy in Mice using Adenovirus Vectors Expressing Human TNFa, J. Oncol., 12 (1998) 509–515.

8  Gillio-Tos A., Cignetti A., Rovera G., Foa R., Retroviral Vector-Mediated Transfer of the Tumor Necrosis Factor Alpha Gene into Human Cancer Cells Restores an Apoptotic Cell Death Program and Induces a Bystander-killing Effect, Blood, 87 (1996) 2486–2495.

9  Walther W., Stein U., Pfeil D., Gene Transfer of Human TNF Alpha into Glioblastoma Cells Permits Modulation of mdr1 Expression and Potentiation of Chemosensitivity, Int. J. Cancer, 61 (1995) 832–839.

10  Kirkpatrick C.H., Activity and Characteristics of Transfer Factors, Biotherapy, 9 (1996) 13–16.

11  Bomford D., Moreno J., Mechanisms of the Anti-tumor Effect of Glucans and Fructosans: A Comparison with C, Parvum. Br. J. Cancer, 36 (1997) 4148–4153.

12  Kawasaki M., Inhibition of Kappa-casein Glycomacropeptide and Lactoferrin of Influenza Virus Hemagglutination, Int. J. Cancer, 57 (1993) 1214–1215.

13  Marchetti J., Metal Complexes of Bovine Lactoferrin Inhibit in Vitro Replication of Herpes Simplex Virus Type 1 and 2, BioMetals, 11 (1994) 89–94.

14  Gutman J., Schettini S. The Ultimate GSH Handbook,  Gutman and Schettini, Montreal, 1998,

15  Baruchel S., Viav G., Olivier R., Bounous G., Wainberg M.Nutraceutical Modulation of GSH with a Humanized Native Milk Serum Protein Isolate, Immunocal: Application AIDS and Cancer is Oxidative Stress and Redox Regulation: Cellular Signaling, AIDS, Cancer and other Diseases. Symposium, Institute Pastuer, 1996,

16  Bounous G., Gold P., The Biological Activity of Undenatured Whey Proteins: Role of Glutathione, Clin. Invest Med., 14 (1991) 296–309.

17  Kennedy R.S., Konok G.P., Bounous G., Baruchel S., Lee TD., The Use of a Whey Protein Concentrate in the Treatment of Patients with Metastatic Carcinoma: A Phase I-II Clinical Study, Anticancer Res., 15 (1995) 2643–2649.

18  Bounous G., Papenburg R., Kongshavn P.A., Gold P., Fleiszer D., Dietary Whey Protein Inhibits the Development of Dimethylhydrazine Induced Malignancy, Clin. Invest Med., 11 (1998) 213–217.

19  Tisdale M.J., Cancer Cachexia, Anti-Cancer Drugs, 4 (1993) 115–125.

20  Georgiev V.N., Durnev A.D., Seredenin S.B., [?] Ubiquinones and the Body's Antimutagenic Defense, Voprosy Meditsinskoi Khimii, 40 (1994) 8–9.

21  Tajimaand M., Toguchi M., Role of Hydrogen Peroxide for Cell Death Induction by Sodium 5,6-Benzylidene-L-ascorbate, Anticancer Res., 18 (1998) 1697–1702.

22  Matsuda T., Kuroyanagi M., Sugiyama S., Umehara K., Ueno A., Nishi K., Role of Hydrogen Peroxide for Cell Death Induction by Sodium 5,6-Benzylidene-L-ascorbate, Chem. Pharm. Bull, 6 (1994) 1216–1225.

23  Mizuno M., Minato K., Ito H., Kawade M., Terai H., Tsuchida H., Anti-tumor Polysaccharide from the Mycelium of Liquid-cultured Agaricus Blazei Mill, Biochem. Mol. Biol. Int., 47 (1999) 707–714.

24  Fujimiya Y., Suzuki Y., Katakura S., Ebina T., Tumor-specific Cytocidal and Immunopotentiating Effects of Relatively Low Molecular Weight Products Derived from the Basidiomycete, Agaricus Blazei Murill, Anticancer Res., 19 (1999) 113.

25  Fujimiya Y., Suzuki Y., Oshiman K., Kobori H., Moriguchi K., Nakashima H., Matumoto Y., Takahara S., Ebina T., Katakura R., Selective Tumoricidal Effect of Soluble Proteoglucan Extracted from the Basidiomycete, Agaricus Blazei Murill, Mediated via Natural Killer Cell Activation and Apoptosis, Cancer Immunol Immunother, 46 (1998) 147–159.

26  Takaku T., Kimura Y., Okuda H., Selective Tumoricidal Effect of Soluble Proteoglucan Extracted from the Basidiomycete, Agaricus Blazei Murill, Mediated via Natural Killer Cell Activation and Apoptosis, J. Nutr., 131 (2001) 1409–1413.

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Explanation of Transfer Factors

Have you ever wondered how many components of your body and immune system know what to do and when to do it? When a bacterium, virus or fungus enters your body, dozens of immune system cells, molecules and body chemicals move into action.... more

Transfer Factors Safety

From April 1974 to January 1999, using transfer factors produced in our laboratories, we treated a total of 1647 patients (pts) suffering from persistent viral infections.... more

Transfer Factors and Cytokines

Transfer factors are proteins that transfer the ability to express cell-mediated immunity from immune donors to non-immune recipients...... more

Dr. See's Study on Transfer Factors

Twenty patients, 12 men and 8 women, were selected for this in vivo study. The average age was 49.3. The twenty individuals were each level 3 or level 4 cancer patients..... more

Dr. See's Abstract and Peer Review on Transfer Factors

Natural products may increase cytotoxic activity of Natural Killer Cells (NK) Tumor Necrosis Factor alpha (TNF-a) while decreasing DNA damage in patients with late-stage cancer.... more

Russian Studies on Transfer Factors

Objective: To determine the extent to which enhanced transfer factors increases Natural Killer (NK) cell activity above baseline...... more

Transfer Factors and Premature Aging

The November 27, 2006 issue of the AMA journal Archives of Internal Medicine published the finding of researchers from Cornell University, Johns Hopkins, the University of Michigan, and the National Institute on Aging that older women with reduced levels of vitamin B6, vitamin B12 and selenium had a greater risk of developing disability in their activities of daily living over a three year follow-up period than those with higher levels. ... more